CPSP, previously known as Dejerine-Roussy syndrome and thalamic pain syndrome, is a feared complication of cerebrovascular accidents and has been. Stroke and pain can sometimes result in Dejerine-Roussy syndrome. Available treatments include antidepressants, anticonvulsants, and. Due to the high clinical variability in presentation of Déjerine-Roussy syndrome, it is impossible to predict which patients with a thalamic stroke will develop pain.

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Journal of the Neurological Sciences. Review Central poststroke pain: The final product of this communication is the ability to see, hear or feel something as interpreted by the brain. Workup should be performed by a neurologist and brain imaging to look for evidence of infarction or tumor should be obtained. Since then, the thalamic syndrome has not ceased to arouse the attention of neurologists, who have developed four major themes: Later on, the disorder came to be labelled Dejerine-Roussy syndrome after the two French neurologists who described the so-called thalamic syndromewhich included a pain component.

Central post-stroke pain due to injury of the spinothalamic tract in patients with cerebral infarction: The disinhibition of temperature-sensing fibers primarily those that sense cold might be the cause of cold allodynia.

Some affected individuals may experience short bursts of sharp, excruciating pain, which has been compared to the pain that occurs when a dental probe strikes an exposed nerve. Intracerebral hemorrhage can precede central post-stroke pain in the legs because of the pattern of arrangement of fibers to face, arm, trunk, and leg is mediolateral, in the ventral posterior nucleus of the thalamus. Chorea Dystonia Parkinson’s disease.


Extradurally means that the paddle is placed on the dura mater, the outermost layer of the membranes meninges that line the brain and spinal cord. StatPearls Publishing ; Jan. The right and left hemispheres of the brain both play important roles in the sensory input and output. The onset of central pain syndrome can vary from days to weeks to months or more than a year after injury to the central nervous system.

For example, affected individuals may experience pain when touched, even when lightly touched. Alleviation of thalamic pain by cilostazol administration: Opioids If antidepressants and anticonvulsants are not effective alone or in combination opioids may be considered. Central pain was first described in by German neurologist L.

Affilations rlussy University of Missouri, Columbia. November Learn how and when to remove this template message. The thalamus is generally believed to relay sensory information between a variety of subcortical areas and the cerebral cortex.

Prognosis Central post-stroke pain is a persistent pain and may be life-long. Migraine Familial hemiplegic Cluster Tension. For the last thirty years, experience has accumulated on the semiology of lesions affecting the nuclei of convergence.

[Dejerine-Roussy syndrome].

Confirmation of a central nervous system lesion through imaging or negative or positive sensory signs confined to the area of the body corresponding to the lesion. Dejerine—Roussy syndrome is most commonly preceded by numbness in the affected side.


Thank you for updating your details. For years, it was believed that the majority of cases of central pain syndrome were due to damage of the thalamus most often caused by a stroke.

Central post-stroke pain roussg often split into three components. The syndrome was named after them after their deaths. Recent advances in the field of spinal cord injury suggest that removal of an injured segment of the spinal cord, wherever feasible, accompanied by vertebrectomy or multiple discectomies might benefit both motor and sensory recovery.

Focal Generalised Status epilepticus Myoclonic epilepsy. Most patients experiencing allodynia, experience pain with touch and pressure, however some can be hypersensitive to temperature.

Amitriptyline is an antidepressant. Itching pruritus has also been reported in individuals with central pain syndrome. Extra-axial Epidural Subdural Subarachnoid.

Although there are many contributing factors and risks associated with strokes, there are very few associated with Dejerine—Roussy syndrome and thalamic lesions specifically.

[Dejerine-Roussy syndrome].

Symptoms of peripheral neuropathic pain orussy. Antiplatelet medications especially cilostazol may have a role in the treatment of central post-stroke pain. Support Center Support Center.