Langerhans cell histiocytosis: a rare cause of cholestasis in adult patients. Case report. Histiocitosis de Langerhans: causa infrecuente de colestasis en el. a Unidad Médico-Quirúrgica de Enfermedades Respiratorias. Área de Neumopatías Intersticiales y Ocupacionales. Hospital Universitario Virgen del Rocío. Abstract. GOMEZ, ANA MARÍA et al. Langerhans cell histiocytosis in children. A description of 10 cases. CES Med. [online]. , vol, n.2, pp

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Langerhans cell histiocytosis was confirmed in both cases ed S immunohistochemical staining. Previous article Next article. Open biopsy for chronic diffuse infiltration lung disease: You can change the settings or obtain more information by clicking here. This item has received.

So far, the patients have not presented any organ involvement by LCH. Print Send to a re Export reference Mendeley Statistics. September Pages Accumulations of histiocytes are normally accompanied by fibrosis and a chronic inflammatory with a remarkable number of eosinophils 4,5.

SRJ is a prestige metric based on the idea that not all citations are the same. CiteScore measures average citations received per document published. When liver involvement is very important, however, and the above treatments could be toxic, the most effective option is liver transplant, which has low post-transplant relapse.

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How to cite this article. Three histological patterns have been described: N Engl J Med,pp. However, if risk organs are involved, other chemotherapeutics are needed as well 6-mercaptopurine and metotrexate.

Histiocitosis de células de Langerhans en niños. Descripción de 10 casos

In the course of the disease, pruritic erythematic lesions with papules appeared on the skin of the patient’s torso. Subscribe to our Newsletter. Journal of Gastrointestinal and Liver Disease ; 15 1: Dear Editor, We present a 42 year old man, with a history of central diabetes insipidus since childhood, primary hyperthyroidism with negative antibodies and seizures since early adulthood. Are you a health professional able to prescribe or dispense drugs?


The pathological diagnosis was chronic pancreatitis. The goal with the description of this cases series is to highlight the importance and awareness to a timely diagnosis and management of this entity, for a better quality of life and longer survival.

SNIP measures contextual citation impact by wighting citations alngerhans on the total number of citations in a subject field. Pediatric Blood and Cancer ; 49 5: To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior.

Solitary congenital self-healing Langerhans cells histiocytosis. Surgery is the accepted therapy for space-occupying lesions. SNIP measures contextual citation histilcitosis by wighting citations based on the total number of citations in a subject field.

There is no standard therapy in adults due to the low number of existing cases, so treatment will depend on the degree of involvement.

April Pages All manuscripts are sent to peer-review and handled by the Editor or an Associate Editor from the team. Dina J, et al. From Monday histiociosis Friday from 9 a. Spanish pdf Article in xml format Article references How to cite this article Automatic translation Send this article by e-mail.

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Relapsing nodular lesions in the course of adult pulmonary Langerhans cell histiocytosis. Blanco 1C.

The patient’s liver function gradually worsened and he was taken to a centre langeerhans reference for a liver transplant, he died before it could be performed.

Langerhans cell histiocytosis in children. The main pathological finding is the presence of an accumulation of Langerhans histiocytes, which have distinctive nuclei features a central “coffee bean” shaped folding, fine chromatin, and oval shaped nuclei that distinguishes them from conventional histiocytes.

The diagnosis is based on pathological study of a biopsy of the organ involved. Liver transplantation in an adult with sclerosing cholangitis due to Langerhans cell histiocytosis. Case report Histiocitosis de Langerhans: Chest,pp. Modern Pathology ; 12 4: In the diagnosis by immunohistochemistry identified Langerhans Cell Histiocytosis, the cases were classified as multisystemic -multifocal in 5 patients, unisystemic in langefhans patients – unifocal unisystemic in 1 patients -multifocal eosinophilic granuloma in 3 patients.

Langerhans cell lanerhans infiltration into pancreas and kidney.


CiteScore measures average citations received per document published. Translators working for the Journal are in charge of the corresponding translations. Bravo 1M. One year before coming to d hospital for the first time, he had presented an episode of acute pancreatitis with pseudocyst formation. Vidal Serrano aE.